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HISTORY

The ZOMES conferences have a long history and tradition. Every conference is unique in its location and main slogans reflecting new development of the research field. The biannual conference series originated as an initiative of scientists studying three related major protein complexes, the 19S proteasome, the COP9 signalosome, and the translation initiation factor eIF3 - called PCI complexes or the “ZOMES”. ZOMES I, held in Israel in 1999, brought together researchers from different fields with common interests in these protein complexes, presented their common or different cellular functions in e. g. development, cell signaling, cell cycle, proteolysis and protein translation. The ZOMES conferences are interactive because they bundle scientists working on evolutionary different organisms. The following ZOMES conferences took place (see below):

ZOMES

Year       

Country

Topic/Subtitle

I

1999

Israel

(Maagan)

The COP9 signalosome, proteasome, and eIF3 at the crossroads of signaling

II

2002

Turkey

(Kemer)

The COP9 signalosome, proteasome, and eIF3 at the crossroads of signaling

III

2004

Germany

(Berlin)

The COP9 signalosome, proteasome, and eIF3: at the interface between signaling and proteolysis

IV

2006

USA

(Yale)

The COP9 signalosome, proteasome, and eIF3: at the interface between signaling and proteolysis

V

2008

Japan (Yokohama)

The COP9 signalosome, proteasome, and eIF3: at the interface between signaling and proteolysis

VI

2010

Israel

(Safed)

Expanding the PCI family beyond proteasome, CSN and eIF3

VII

2012

Germany

(Munich)

Ubiquitin-like proteins and their respective PCI complexes

VIII

2014

China

(Xiamen)

From system dynamics to biology: Expanding the realm of PCI complexes

IX

2017

Italy

(Rome)

PCI complexes and ubiquitin defining a hub for protein homeostasis

X

2019

Israel

(Akko)

The broader cellular impact of PCI complexes

XI

2022

Germany

(Magdeburg)

PCI Complexes - Determining Cell Physiology By Setting The Course In Protein Turnover